Tony Cingrani (3-0), filling in for the injured Johnny Cueto, pitched seven strong innings as Cincinnati extended its franchise-best winning streak at Wrigley Field to 11 games. Cingrani, from Chicago's South Suburbs, allowed two runs and four hits, while striking out five and allowing one walk.
Garza (1-1) was tagged for a career-high nine runs and nine hits in five-plus innings. He was lifted in the sixth after allowing six runs without retiring a batter. Garza dropped to 0-2 against the Reds this season, allowing 13 runs in nine innings. The three homers he gave up were the most since last July 5 at Atlanta.
Cody Ransomhit a solo home run for the Cubs, who have lost seven of their last nine games. The third baseman committed three of Chicago's four errors as the Cubs suffered their worst defeat of the season.
With two outs in the second, Frazier connected on a 1-2 pitch that wound up in the center-field basket for his seventh home run of the season. It was his first homer on the road this year and first one since April 24th.
An inning later, Votto tagged Garza for a two-run shot. It was Votto's 11th of the season. Votto is 16 for 30 with seven doubles, one home run and eight RBIs during a nine-game hitting streak at Wrigley.
The Reds added six runs for Cingrani in the sixth. Jay Brucelined a double down the left-field line to drive in two runs. After Garza hit Frazier with a pitch, Paul followed with a three-run homer to right. After chasing Garza, Cozart added an RBI single to give the Reds a 9-1 lead.
Bruce was 3 for 5 with two RBIs as Cincinnati finished with 17 hits.
Ransom scored on Alfonso Soriano's sacrifice fly in the fourth. Ransom hit his seventh homer of the season in the sixth.
Cozart cleared the bases on a three-run homer in the eighth inning off Cubs reliever Zach Putnam. Putnam left with an apparent injury after giving up the home run.